Noun
1. a state of separation between persons or groups
2. the act of isolating something; setting something apart from others
3. a feeling of being disliked and alone
4. preference for seclusion or isolation
5. (psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it
6. a country's withdrawal from internal politics;
"he opposed a policy of American isolation"